The laboratory mouse has emerged as the preeminent model for human and animal genomics research, building upon its well-established role in biomedical sciences. Although mice are well defined genetically and their genome can be precisely manipulated, effective mouse research requires a global approach to this complex research species. The University of California, Davis Mouse Biology Program (MBP) is an evolving program of excellence that is built upon the campus' exceptional strengths in biological science, veterinary medicine, and human medicine. These strengths are combined within the Center for Comparative Medicine, a unique research and teaching center that provides the intellectual and administrative oversight of the MBP. These goals are being developed within the context of the teaching mission of the University, providing outstanding opportunities for training in comparative medicine. The MBP serves the UC Davis campus, the western region, and the nation, with growing international linkages. The following pages feature advanced technical services, and opportunities in teaching and research collaborations that are available to our partners in science. We welcome your input in helping us build a MBP that meets your needs.